Pyridium (phenazopyridine hydrochloride)
Urinary tract analgesic
Symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.
Irritation of Lower Urinary Tract Mucosa
Symptomatic Relief of Pain, Burning, Urgency, Frequency, and Other Discomforts Caused by Infection, Trauma, Surgery, Endoscopic Procedures, or Passage of Sounds/Catheters:
Usual: 200mg tid
Max Duration: 2 days, when used concomitantly w/ an antibacterial agent for treatment of UTI
Tab: 100mg, 200mg
D/C when symptoms are controlled. A yellowish tinge of the skin/sclera may indicate accumulation due to impaired renal excretion and the need to d/c therapy. Produces a reddish-orange discoloration of the urine and may stain fabric; staining of contact lenses reported. May interfere with urinalysis based on spectrometry or color reactions.
Headache, rash, pruritus, GI disturbance, anaphylactoid-like reaction.
PREGNANCY AND LACTATION
Category B, safety not known in nursing.
MECHANISM OF ACTION
Urinary tract analgesic; has not been established. Excreted in urine where it exerts a topical analgesic effect on urinary tract mucosa.
Elimination: Urine (as much as 66% unchanged).
Assess for previous hypersensitivity to the drug, renal insufficiency, cause of urinary pain, and pregnancy/nursing status.
Monitor for control of symptoms, development of yellowish tinge of the skin/sclera, and other adverse reactions.
Inform that drug produces a reddish-orange discoloration of urine and may stain fabric and contact lenses.
20-25°C (68-77°F); excursions permitted to 15-30°C (59-86°F).
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