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Nizoral 2% (ketoconazole)


Azole antifungal




Treatment of tinea (pityriasis) versicolor caused by Pityrosporum orbiculare (also known as Malassezia furfur or M. orbiculare).


Fungal Infections

Tinea (Pityriasis) Versicolor Caused by Pityrosporum Orbiculare:
Apply once to the damp skin of the affected area and a wide margin surrounding this area


Topical route

Lather, leave in place for 5 min, and then rinse off with water


Shampoo: 2% [4 fl. oz.]


Severe hypersensitivity reactions, including anaphylaxis, reported. D/C if a reaction suggesting sensitivity or chemical irritation occurs.


Abnormal hair texture, scalp pustules, skin dryness, itching, oily/dry hair and scalp, pruritus, application-site reaction.


Category C, caution in nursing.


Azole antifungal; impairs the synthesis of ergosterol, which is a vital component of fungal cell membranes.


Assess for hypersensitivity to the drug and pregnancy/nursing status.


Monitor for hypersensitivity reactions, chemical irritation, and other adverse reactions.


Inform that shampoo may be irritating to mucous membranes of the eyes and that contact with this area should be avoided. Advise that hair discoloration and abnormal hair texture, removal of the curl from permanently waved hair, itching, skin burning sensation and contact dermatitis, hypersensitivity, angioedema, alopecia, rash, urticaria, skin irritation, dry skin, and application-site reactions may occur. Instruct to d/c therapy and contact physician immediately if allergic reactions (eg, generalized rash, skin reactions, severe swelling, angioedema, SOB) develop.


≤25°C (77°F). Protect from light.


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