Buy Elocon Online

Elocon (mometasone furoate)

THERAPEUTIC CLASS

Corticosteroid

DEA CLASS

RX

INDICATIONS

(Cre, Oint) Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients ≥2 yrs of age. (Lot) Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients ≥12 yrs of age.

ADULT DOSAGE

Inflammatory and Pruritic Manifestations of Corticosteroid-Responsive Dermatoses

Cre/Oint:
Apply a thin film to affected skin areas qd

Lot:
Apply a few drops to affected skin areas qd and massage lightly until it disappears

Cre/Lot/Oint:
D/C therapy when control is achieved; reassess diagnosis if no improvement seen w/in 2 weeks

PEDIATRIC DOSAGE

Inflammatory and Pruritic Manifestations of Corticosteroid-Responsive Dermatoses

≥2 Years:
Cre/Oint:
Apply a thin film to affected skin areas qd; safety and efficacy for >3 weeks have not been established

≥12 Years:
Lot:
Apply a few drops to affected skin areas qd and massage lightly until it disappears

Cre/Lot/Oint:
D/C therapy when control is achieved; reassess diagnosis if no improvement seen w/in 2 weeks

ADMINISTRATION

Topical route

Avoid use with occlusive dressings unless directed by physician
Should not be applied in the diaper area if the child still requires diapers or plastic pants, as these garments may constitute occlusive dressing

HOW SUPPLIED

Cre: 0.1% [15g, 50g]; Lot: 0.1% [30mL, 60mL]; Oint: 0.1% [15g, 45g]

WARNINGS/PRECAUTIONS

Not for oral, ophthalmic, or intravaginal use. Avoid use on the face, groin, or axillae. Avoid use with occlusive dressings. Systemic absorption may produce reversible hypothalamic pituitary adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria. Periodically evaluate for HPA-axis suppression and, if noted, gradually withdraw drug, reduce frequency of application, or substitute a less potent corticosteroid. Factors predisposing to HPA-axis suppression include use of high-potency steroids, large treatment surface areas, prolonged use, use of occlusive dressings, altered skin barrier, liver failure, and young age. Glucocorticosteroid insufficiency may occur, requiring supplemental systemic corticosteroids. Pediatric patients may be more susceptible to systemic toxicity. D/C and institute appropriate therapy if irritation develops. Use appropriate antifungal or antibacterial agent if concomitant skin infections are present or develop; if favorable response does not occur promptly, d/c until infection is controlled. Caution in elderly. (Cre/Oint) Safety and efficacy of use in pediatric patients for >3 weeks have not been established.

ADVERSE REACTIONS

Burning, irritation, dryness, secondary infection, acneiform reaction, folliculitis, hypertrichosis, hypopigmentation, perioral dermatitis, allergic contact dermatitis, striae, miliaria, skin atrophy.

PREGNANCY AND LACTATION

Category C, caution in nursing.

MECHANISM OF ACTION

Corticosteroid; not established. Possesses anti-inflammatory, antipruritic, and vasoconstrictive properties. Suspected to act by the induction of phospholipase A2 inhibitory proteins called lipocortins, which control the biosynthesis of potent mediators of inflammation (eg, prostaglandins, leukotrienes) by inhibiting the release of arachidonic acid.

PHARMACOKINETICS

Absorption: Percutaneous; extent of absorption is determined by vehicle and integrity of the epidermal barrier. Distribution: Found in breast milk (systemically administered).

ASSESSMENT

Assess for presence of concomitant skin infections, severity of dermatoses, factors that predispose to HPA-axis suppression, and pregnancy/nursing status.

MONITORING

Monitor for signs/symptoms of HPA-axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, irritation, allergic contact dermatitis (eg, failure to heal), skin infections, and other adverse reactions. Perform periodic monitoring of HPA-axis suppression using adrenocorticotropic hormone stimulation test. Monitor for systemic toxicity (eg, adrenal suppression, intracranial HTN) in pediatric patients. Monitor response to therapy.

PATIENT COUNSELING

Instruct to use externally ud. Advise not to use on face, underarms, or groin areas. Instruct to avoid contact with eyes. Advise not to use for any disorder other than that for which it was prescribed. Inform not to bandage, cover, or wrap treated skin area unless directed by a physician. Instruct to report any signs of local adverse reactions to physician. Advise not to use medication for treatment of diaper dermatitis and not to apply to diaper area. Instruct to d/c use when control is achieved and to notify physician if no improvement seen within 2 weeks. Advise that other corticosteroid-containing products should not be used without first consulting with the physician.

STORAGE

25°C (77°F); excursions permitted to 15-30°C (59-86°F). (Cre) Avoid excessive heat.

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